Microvascular effects of atrial natriuretic factor: interaction with alpha 1- and alpha 2-adrenoceptors.
نویسندگان
چکیده
منابع مشابه
Faber , D R Gettes and D P Gianturco 2 - adrenoceptors . Microvascular effects of atrial natriuretic factor : interaction with alpha 1 - and alpha
2-adrenoceptors. Microvascular effects of atrial natriuretic factor: interaction with alpha 1and alpha Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 1988 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.63.2.415 1988;63:415-428 Circ Res. http://circr...
متن کاملMicrovascular Effects of Atrial Natriuretic Factor : Interaction With ax - and a 2 - Adrenoceptors
The cremaster skeletal muscle of anesthetized rats was denervated and extended with intact circulation into a tissue bath. Intravital microscopy was used to measure microvessel diameter at three different anatomical levels within the microcirculation: large distributing arterioles (x control diameter = 100 ± 7 /nn), large capacitance venules (147 ± 8 /tin), and small terminal arterioles (17 ± 1...
متن کاملEffects of alpha-human atrial natriuretic peptide in essential hypertension.
Because there is little published information on the effects of atrial peptides in hypertensive humans, 100 micrograms of alpha-human atrial natriuretic peptide was injected intravenously into six patients with essential hypertension in a double-blind, placebo-controlled study under standardized conditions of body posture and dietary sodium and potassium intake. The peptide increased urine sodi...
متن کاملInteraction Between Microvascular a 1 - and a 2 - Adrenoceptors and Endothelium - Derived Relaxing Factor
Intravital microscopy was used to study the effect of endothelium-derived relaxing factor (EDRF) on microvascular adrenoceptor sensitivity in rat cremaster skeletal muscle. NG-Monomethyl L-arginine (L-NMMA, 1-300 ,uM), an inhibitor ofEDRF formation, produced concentration-dependent constriction of arterioles and venules. When an intermediate amount of a-l versus a2-adrenoceptor tone was first p...
متن کاملAlpha 1-adrenoceptors in human corneal epithelium.
Specific binding of the potent, selective alpha 1-adrenoceptor antagonist 3H-prazosin was demonstrated in cultured human corneal epithelial cells. Specific binding of the radioligand was concentration-dependent between 0.5 and 6 nM, with apparent saturation of receptor sites seen at higher concentrations. The cells exhibited a maximum binding capacity for 3H-prazosin of 225 fmol/mg of cellular ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1988
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.63.2.415